iS Clinical Retinol+ Emulsion 0.3
iS Clinical Retinol+ Emulsion 0.3 is a 1 oz night emulsion built on a retinol iS Clinical describes as being of botanical origin, encapsulated with bio-identical lipids, alongside a proprietary blend of bakuchiol. The 0.3 in the name is the retinol strength. iS Clinical does not print a percentage on its product page, and it states "RETINOL 0.3% and 1.0%" in its own Retinol+ Emulsions trade notes, where 0.3 and 1.0 are the two strengths in the line. We stock the 0.3. It sits with firming treatments across brands.
iS Clinical's benefit list for it: reduces the appearance of fine lines and wrinkles, diminishes the appearance of uneven skin tones, textures and blemishes, protects from environmental and oxidative stressors with Extremozyme technology, strengthens and hydrates the skin, and increases firmness and elasticity. Those are iS Clinical's claims, not measured outcomes.
On evidence, iS Clinical's trade notes go further than its product page. They describe gene-activation work for both strengths, and for the 0.3 a subject study with ultrasound imaging, quoting "There was a statistically significant and continuing increase in the absolute amount of skin density". What the notes do not give is a panel size, a duration, or a single number. So there is study material, and there is nothing in it you can check.
Because iS Clinical names blemishes in its own benefit list, this also sits in our picks for blemish-prone skin.
| Size | 1 oz / 30 g |
| Form | Night emulsion |
| Named by iS Clinical | Retinol of botanical origin encapsulated with bio-identical lipids, bakuchiol, ectoin |
| Retinol percentage | 0.3%, stated in iS Clinical's trade notes and not on its product page |
| In the ingredient list | Ectoin at 6, bakuchiol at 14, retinol at 17, of roughly 70 |
| Fragrance | Fragrance/Parfum, last in the list |
| Routine step | Evening, every 3 days for 3 weeks, then every 2 days if tolerated |
| Brand | iS Clinical |
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